Collaborative Projects

MODERN: Understanding and modelling reservoirs, vehicles and transmission of ESBL-producing Enterobacteriaceae in the community and long term care facilities

Antibiotic-resistant germs are a serious problem in many hospitals and care facilities. The aim of this collaborative project is to characterize the occurrence, transmission dynamics and the risk factors for catching these germs in long term care facilities. This will take place in several European countries with different rates of bacterial resistance. The research focuses on the pathogen Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae (ESBL-PE).

It is expected to provide comprehensive information about the key aspects of the transmission determinants of ESBL-PE. Transmission paths and factors will be studied within private households after a family member has been colonized or infected with ESBL-PE in a hospital or care facility. The research will also document the extent to which ESBL-PE spreads via wastewater and food. The results will be used for computer-aided modelling of the transmission dynamics of ESBL-PEs. Furthermore, the information gained in this way is to be used to model the spread of the pathogen. The latter models will in turn serve as a basis for developing infection control programmes.